General Dentistry is AGD's peer-reviewed journal. Published bimonthly, General Dentistry presents research and clinical findings to support the full range of procedures that general dentists perform on a regular basis.
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July/August 2021
Table of Contents
Departments
-
Editorial The greater good
Timothy F. KosinskiFull Article (PDF)
2021 July/August; 69(4):6.
-
Esthetics Minimally invasive correction of a fractured anterior crown using combination treatment
Wynn OkudaFull Article (PDF)
2021 July/August; 69(4):7-9.
-
Prosthodontics Conversion of a bar overdenture to an attachment-only overdenture
Samuel M. StrongFull Article (PDF)
2021 July/August; 69(4):10-13.
-
Pharmacology Tramadol: what have we learned in the last 25 years?
Mark DonaldsonFull Article (PDF)
Jason H. Goodchild
2021 July/August; 69(4):14-18.
-
Oral Diagnosis Unilocular maxillary lesion and Painless lump on the mandible
Galal OmamiFull Article (PDF)
2021 July/August; 69(4):76,78.
-
Self-Instruction Answers Exercises No. GD459, GD460, and GD461 from the July/August 2020 issue
2021 July/August; 69(4):79.Full Article (PDF)
Clinical Articles
-
SELF-INSTRUCTION
Basic Science Evaluation of a mucoadhesive pilocarpine tablet for the treatment of xerostomia: a randomized, double-blind, crossover clinical trial
George Mário de Araújo Silva GusmãoFull Article (PDF)
Patrícia Mendonça Borba
Marcela de Aguiar Galindo
Laura de Fátima Souto Maior
Luiz Alcino Monteiro Gueiros
Jair Carneiro Leão
José Lamartine Soares Sobrinho
Alessandra de Albuquerque Tavares Carvalho
A randomized, double-blind, crossover clinical trial was conducted to evaluate the effectiveness of a mucoadhesive, controlled-release tablet of pilocarpine for the treatment of xerostomia in older adults. Tablets with or without pilocarpine relieved patients’ dry mouth symptoms and increased unstimulated salivary flow, but stimulated salivary flow was increased only when tablets containing pilocarpine were administered.
2021 July/August; 69(4):19-26.
Self-Instruction Exercise No. GD477 -
SELF-INSTRUCTION
Restorative Dentistry Use of smartphones and tablets in radiographic evaluation: accuracy of caries detection on bitewing radiographs
Cristinne Andrade MeloFull Article (PDF)
Marcos Antônio Lima dos Santos
Liciane dos Santos Menezes
Francielle Santos de Santana
Maria de Fátima Batista de Melo
Wilton Mitsunari Takeshita
This study compared the accuracy of tablet and smartphone displays to that of a calibrated LCD monitor for the detection of incipient caries on bitewing radiographs. The Pavilion dm1 notebook computer, iPhone 6s, Galaxy Gran2 Duos, iPad, and Galaxy Tab did not present statistically significant differences in diagnostic accuracy, suggesting that all of these displays can be used to detect incipient caries on bitewing radiographs.
2021 July/August; 69(4):28-34.
Self-Instruction Exercise No. GD478 -
Special Patient Care Pretransplantation and posttransplantation considerations in the oral healthcare of a patient with non-Hodgkin B-cell lymphoma: a case report
Ross TeicherFull Article (PDF)
Marc Henschel
This case report discusses considerations for oral rehabilitative treatment before and after hematopoietic stem cell transplantation in patients with non-Hodgkin B-cell lymphoma. The patient’s complicated medical history made dental treatment difficult, but careful attention to known considerations for patients undergoing stem cell therapy ensured maintenance of the patient’s oral health.
2021 July/August; 69(4):36-40.
-
SELF-INSTRUCTION
Esthetics/Cosmetic Dentistry Conservative approach to treating severe tetracycline staining: a 12-month follow-up
Rafael Santos RochaFull Article (PDF)
Maurício Yugo de Souza
Victor Ruano
Eduardo Bresciani
This case report describes minimally invasive treatment with a combination of at-home and in-office dental bleaching and direct restorations to improve the esthetics of tetracycline-stained teeth in a 44-year-old woman.
2021 July/August; 69(4):41-44.
Self-Instruction Exercise No. GD479 -
Special Patient Care Association of anxiety, depression, and stress with burning mouth syndrome: a case-control study
Cássia Emanuella Nóbrega MaltaFull Article (PDF)
Fábio Wildson Gurgel Costa
Camila Costa Dias
Anna Clara Aragão Matos Carlos
Fabrício Bitu Sousa
Paulo Goberlânio de Barros Silva
Carolina Rodrigues Teófilo
Burning mouth syndrome (BMS) is a painful disorder involving severe burning in the oral cavity in the absence of clinical signs. In this study, 60 patients were allocated to 3 groups: patients with BMS, patients with benign changes in the oral cavity, or healthy patients. Anxiety was independently associated with a 123.8 times greater risk of having BMS.
2021 July/August; 69(4):46-52.
-
Basic Science An extrapyramidal reaction presenting as an acute temporomandibular episode: a case report
William R. BachandFull Article (PDF)
A patient with sudden onset of severe jaw muscle spasms, facial grimacing, and difficulty speaking was found to be experiencing an adverse reaction to prochlorperazine (Compazine), which can cause extrapyramidal reactions. This case highlights the importance of obtaining an accurate history and being aware of possible adverse effects of medications.
2021 July/August; 69(4):54-55.
-
Periodontics Applying basic math to periodontal decision-making
Ben BaleviFull Article (PDF)
This review provides an introduction to analysis of clinical measures of uncertainty and statistical concepts to aid clinicians in using evidence-based dentistry.
2021 July/August; 69(4):56-63.
-
Oral and Maxillofacial Surgery Quality of life of patients following orthognathic surgery
Gilberto HeinzmannFull Article (PDF)
João Paulo De Carli
Silvana Alba Scortegagna
Aline Hübner da Silva
Alexandra Oliveira Keller
Marcos Eugenio de Bittencourt
Julia Zandoná
Maria Salete Sandini Linden
This study evaluated the quality of life of 10 patients who had undergone orthognathic surgery for a dentofacial deformity. The patients answered a variety of questionnaires on their physical, functional, psychological, and social status after orthognathic surgery, and analysis revealed that surgery resulted in improved quality of life.
2021 July/August; 69(4):64-69.
-
Oral Medicine, Oral Diagnosis, Oral Pathology Probability of oral complications of radiotherapy and chemotherapy for head and neck cancer
Laís Heringer Mendes CoelhoFull Article (PDF)
Clarice Lima Alvares da Silva
Rebeca Cardoso Pedra
Lucas de Paula Lopes Rosado
Francielle Silvestre Verner
Sibele Nascimento de Aquino
An analysis of the records of 400 patients who underwent radiotherapy, chemotherapy, or both for head and neck cancer revealed that 199 patients experienced oral complications associated with treatment. The risk increased when both therapies were performed. Associations were also found between the use of tobacco or alcohol and the rate of oral complications.
2021 July/August; 69(4):70-74.
-
Implants Titanium versus ceramic implants for overdentures: a meta-analysis of prospective studies
Emily Vivianne Freitas da SilvaFull Article (PDF)
Betina Chiarelo Commar
Sandro Basso Bitencourt
Liliane da Rocha Bonatto
Daniela Micheline dos Santos
Ana Beatriz Bueno Carlini Bittencourt
Marcelo Coelho Goiato
The aim of this study was to compare the use of titanium and ceramic implants for overdentures in terms of their failure rates, surface treatments, and marginal bone loss (MBL). The literature was searched using the PubMed, Scopus, and Cochrane databases up to October 2019. Clinical studies in which ceramic and titanium implants for overdentures were compared in terms of their failure rates, surface treatments, and MBL were included in the meta-analysis. The meta-analysis was performed based on the Mantel-Haenszel and inverse variance methods using a fixed-effects model and 95% confidence intervals. A total of 2747 publications were identified after the exclusion of duplicate articles. Fifteen were selected for full-text reading, and 2 were included in the review. Each of the 2 studies initially enrolled 24 patients, and a total of 38 patients (mean age of 62 years) were evaluated at the 1-year follow-up. A total of 112 titanium implants (success rate of 71.1%) and 146 ceramic implants (success rate of 65.9%) were placed. Twenty titanium implants failed, and an associated MBL of 0.15 mm was observed. For ceramic implants, 42 failures occurred, and an associated MBL of 0.33 mm was observed. Titanium implants provided better clinical results (less MBL and lower failure rate) for the support of overdentures than did ceramic implants.
2021 July/August; 69(4):e1-e5.
2016
July/August 2021
Table of Contents
Departments
-
Editorial The greater good
Timothy F. KosinskiFull Article (PDF)
2021 July/August; 69(4):6.
-
Esthetics Minimally invasive correction of a fractured anterior crown using combination treatment
Wynn OkudaFull Article (PDF)
2021 July/August; 69(4):7-9.
-
Prosthodontics Conversion of a bar overdenture to an attachment-only overdenture
Samuel M. StrongFull Article (PDF)
2021 July/August; 69(4):10-13.
-
Pharmacology Tramadol: what have we learned in the last 25 years?
Mark DonaldsonFull Article (PDF)
Jason H. Goodchild
2021 July/August; 69(4):14-18.
-
Oral Diagnosis Unilocular maxillary lesion and Painless lump on the mandible
Galal OmamiFull Article (PDF)
2021 July/August; 69(4):76,78.
-
Self-Instruction Answers Exercises No. GD459, GD460, and GD461 from the July/August 2020 issue
2021 July/August; 69(4):79.Full Article (PDF)
Clinical Articles
-
SELF-INSTRUCTION
Basic Science Evaluation of a mucoadhesive pilocarpine tablet for the treatment of xerostomia: a randomized, double-blind, crossover clinical trial
George Mário de Araújo Silva GusmãoFull Article (PDF)
Patrícia Mendonça Borba
Marcela de Aguiar Galindo
Laura de Fátima Souto Maior
Luiz Alcino Monteiro Gueiros
Jair Carneiro Leão
José Lamartine Soares Sobrinho
Alessandra de Albuquerque Tavares Carvalho
A randomized, double-blind, crossover clinical trial was conducted to evaluate the effectiveness of a mucoadhesive, controlled-release tablet of pilocarpine for the treatment of xerostomia in older adults. Tablets with or without pilocarpine relieved patients’ dry mouth symptoms and increased unstimulated salivary flow, but stimulated salivary flow was increased only when tablets containing pilocarpine were administered.
2021 July/August; 69(4):19-26.
Self-Instruction Exercise No. GD477 -
SELF-INSTRUCTION
Restorative Dentistry Use of smartphones and tablets in radiographic evaluation: accuracy of caries detection on bitewing radiographs
Cristinne Andrade MeloFull Article (PDF)
Marcos Antônio Lima dos Santos
Liciane dos Santos Menezes
Francielle Santos de Santana
Maria de Fátima Batista de Melo
Wilton Mitsunari Takeshita
This study compared the accuracy of tablet and smartphone displays to that of a calibrated LCD monitor for the detection of incipient caries on bitewing radiographs. The Pavilion dm1 notebook computer, iPhone 6s, Galaxy Gran2 Duos, iPad, and Galaxy Tab did not present statistically significant differences in diagnostic accuracy, suggesting that all of these displays can be used to detect incipient caries on bitewing radiographs.
2021 July/August; 69(4):28-34.
Self-Instruction Exercise No. GD478 -
Special Patient Care Pretransplantation and posttransplantation considerations in the oral healthcare of a patient with non-Hodgkin B-cell lymphoma: a case report
Ross TeicherFull Article (PDF)
Marc Henschel
This case report discusses considerations for oral rehabilitative treatment before and after hematopoietic stem cell transplantation in patients with non-Hodgkin B-cell lymphoma. The patient’s complicated medical history made dental treatment difficult, but careful attention to known considerations for patients undergoing stem cell therapy ensured maintenance of the patient’s oral health.
2021 July/August; 69(4):36-40.
-
SELF-INSTRUCTION
Esthetics/Cosmetic Dentistry Conservative approach to treating severe tetracycline staining: a 12-month follow-up
Rafael Santos RochaFull Article (PDF)
Maurício Yugo de Souza
Victor Ruano
Eduardo Bresciani
This case report describes minimally invasive treatment with a combination of at-home and in-office dental bleaching and direct restorations to improve the esthetics of tetracycline-stained teeth in a 44-year-old woman.
2021 July/August; 69(4):41-44.
Self-Instruction Exercise No. GD479 -
Special Patient Care Association of anxiety, depression, and stress with burning mouth syndrome: a case-control study
Cássia Emanuella Nóbrega MaltaFull Article (PDF)
Fábio Wildson Gurgel Costa
Camila Costa Dias
Anna Clara Aragão Matos Carlos
Fabrício Bitu Sousa
Paulo Goberlânio de Barros Silva
Carolina Rodrigues Teófilo
Burning mouth syndrome (BMS) is a painful disorder involving severe burning in the oral cavity in the absence of clinical signs. In this study, 60 patients were allocated to 3 groups: patients with BMS, patients with benign changes in the oral cavity, or healthy patients. Anxiety was independently associated with a 123.8 times greater risk of having BMS.
2021 July/August; 69(4):46-52.
-
Basic Science An extrapyramidal reaction presenting as an acute temporomandibular episode: a case report
William R. BachandFull Article (PDF)
A patient with sudden onset of severe jaw muscle spasms, facial grimacing, and difficulty speaking was found to be experiencing an adverse reaction to prochlorperazine (Compazine), which can cause extrapyramidal reactions. This case highlights the importance of obtaining an accurate history and being aware of possible adverse effects of medications.
2021 July/August; 69(4):54-55.
-
Periodontics Applying basic math to periodontal decision-making
Ben BaleviFull Article (PDF)
This review provides an introduction to analysis of clinical measures of uncertainty and statistical concepts to aid clinicians in using evidence-based dentistry.
2021 July/August; 69(4):56-63.
-
Oral and Maxillofacial Surgery Quality of life of patients following orthognathic surgery
Gilberto HeinzmannFull Article (PDF)
João Paulo De Carli
Silvana Alba Scortegagna
Aline Hübner da Silva
Alexandra Oliveira Keller
Marcos Eugenio de Bittencourt
Julia Zandoná
Maria Salete Sandini Linden
This study evaluated the quality of life of 10 patients who had undergone orthognathic surgery for a dentofacial deformity. The patients answered a variety of questionnaires on their physical, functional, psychological, and social status after orthognathic surgery, and analysis revealed that surgery resulted in improved quality of life.
2021 July/August; 69(4):64-69.
-
Oral Medicine, Oral Diagnosis, Oral Pathology Probability of oral complications of radiotherapy and chemotherapy for head and neck cancer
Laís Heringer Mendes CoelhoFull Article (PDF)
Clarice Lima Alvares da Silva
Rebeca Cardoso Pedra
Lucas de Paula Lopes Rosado
Francielle Silvestre Verner
Sibele Nascimento de Aquino
An analysis of the records of 400 patients who underwent radiotherapy, chemotherapy, or both for head and neck cancer revealed that 199 patients experienced oral complications associated with treatment. The risk increased when both therapies were performed. Associations were also found between the use of tobacco or alcohol and the rate of oral complications.
2021 July/August; 69(4):70-74.
-
Implants Titanium versus ceramic implants for overdentures: a meta-analysis of prospective studies
Emily Vivianne Freitas da SilvaFull Article (PDF)
Betina Chiarelo Commar
Sandro Basso Bitencourt
Liliane da Rocha Bonatto
Daniela Micheline dos Santos
Ana Beatriz Bueno Carlini Bittencourt
Marcelo Coelho Goiato
The aim of this study was to compare the use of titanium and ceramic implants for overdentures in terms of their failure rates, surface treatments, and marginal bone loss (MBL). The literature was searched using the PubMed, Scopus, and Cochrane databases up to October 2019. Clinical studies in which ceramic and titanium implants for overdentures were compared in terms of their failure rates, surface treatments, and MBL were included in the meta-analysis. The meta-analysis was performed based on the Mantel-Haenszel and inverse variance methods using a fixed-effects model and 95% confidence intervals. A total of 2747 publications were identified after the exclusion of duplicate articles. Fifteen were selected for full-text reading, and 2 were included in the review. Each of the 2 studies initially enrolled 24 patients, and a total of 38 patients (mean age of 62 years) were evaluated at the 1-year follow-up. A total of 112 titanium implants (success rate of 71.1%) and 146 ceramic implants (success rate of 65.9%) were placed. Twenty titanium implants failed, and an associated MBL of 0.15 mm was observed. For ceramic implants, 42 failures occurred, and an associated MBL of 0.33 mm was observed. Titanium implants provided better clinical results (less MBL and lower failure rate) for the support of overdentures than did ceramic implants.
2021 July/August; 69(4):e1-e5.
2015
July/August 2021
Table of Contents
Departments
-
Editorial The greater good
Timothy F. KosinskiFull Article (PDF)
2021 July/August; 69(4):6.
-
Esthetics Minimally invasive correction of a fractured anterior crown using combination treatment
Wynn OkudaFull Article (PDF)
2021 July/August; 69(4):7-9.
-
Prosthodontics Conversion of a bar overdenture to an attachment-only overdenture
Samuel M. StrongFull Article (PDF)
2021 July/August; 69(4):10-13.
-
Pharmacology Tramadol: what have we learned in the last 25 years?
Mark DonaldsonFull Article (PDF)
Jason H. Goodchild
2021 July/August; 69(4):14-18.
-
Oral Diagnosis Unilocular maxillary lesion and Painless lump on the mandible
Galal OmamiFull Article (PDF)
2021 July/August; 69(4):76,78.
-
Self-Instruction Answers Exercises No. GD459, GD460, and GD461 from the July/August 2020 issue
2021 July/August; 69(4):79.Full Article (PDF)
Clinical Articles
-
SELF-INSTRUCTION
Basic Science Evaluation of a mucoadhesive pilocarpine tablet for the treatment of xerostomia: a randomized, double-blind, crossover clinical trial
George Mário de Araújo Silva GusmãoFull Article (PDF)
Patrícia Mendonça Borba
Marcela de Aguiar Galindo
Laura de Fátima Souto Maior
Luiz Alcino Monteiro Gueiros
Jair Carneiro Leão
José Lamartine Soares Sobrinho
Alessandra de Albuquerque Tavares Carvalho
A randomized, double-blind, crossover clinical trial was conducted to evaluate the effectiveness of a mucoadhesive, controlled-release tablet of pilocarpine for the treatment of xerostomia in older adults. Tablets with or without pilocarpine relieved patients’ dry mouth symptoms and increased unstimulated salivary flow, but stimulated salivary flow was increased only when tablets containing pilocarpine were administered.
2021 July/August; 69(4):19-26.
Self-Instruction Exercise No. GD477 -
SELF-INSTRUCTION
Restorative Dentistry Use of smartphones and tablets in radiographic evaluation: accuracy of caries detection on bitewing radiographs
Cristinne Andrade MeloFull Article (PDF)
Marcos Antônio Lima dos Santos
Liciane dos Santos Menezes
Francielle Santos de Santana
Maria de Fátima Batista de Melo
Wilton Mitsunari Takeshita
This study compared the accuracy of tablet and smartphone displays to that of a calibrated LCD monitor for the detection of incipient caries on bitewing radiographs. The Pavilion dm1 notebook computer, iPhone 6s, Galaxy Gran2 Duos, iPad, and Galaxy Tab did not present statistically significant differences in diagnostic accuracy, suggesting that all of these displays can be used to detect incipient caries on bitewing radiographs.
2021 July/August; 69(4):28-34.
Self-Instruction Exercise No. GD478 -
Special Patient Care Pretransplantation and posttransplantation considerations in the oral healthcare of a patient with non-Hodgkin B-cell lymphoma: a case report
Ross TeicherFull Article (PDF)
Marc Henschel
This case report discusses considerations for oral rehabilitative treatment before and after hematopoietic stem cell transplantation in patients with non-Hodgkin B-cell lymphoma. The patient’s complicated medical history made dental treatment difficult, but careful attention to known considerations for patients undergoing stem cell therapy ensured maintenance of the patient’s oral health.
2021 July/August; 69(4):36-40.
-
SELF-INSTRUCTION
Esthetics/Cosmetic Dentistry Conservative approach to treating severe tetracycline staining: a 12-month follow-up
Rafael Santos RochaFull Article (PDF)
Maurício Yugo de Souza
Victor Ruano
Eduardo Bresciani
This case report describes minimally invasive treatment with a combination of at-home and in-office dental bleaching and direct restorations to improve the esthetics of tetracycline-stained teeth in a 44-year-old woman.
2021 July/August; 69(4):41-44.
Self-Instruction Exercise No. GD479 -
Special Patient Care Association of anxiety, depression, and stress with burning mouth syndrome: a case-control study
Cássia Emanuella Nóbrega MaltaFull Article (PDF)
Fábio Wildson Gurgel Costa
Camila Costa Dias
Anna Clara Aragão Matos Carlos
Fabrício Bitu Sousa
Paulo Goberlânio de Barros Silva
Carolina Rodrigues Teófilo
Burning mouth syndrome (BMS) is a painful disorder involving severe burning in the oral cavity in the absence of clinical signs. In this study, 60 patients were allocated to 3 groups: patients with BMS, patients with benign changes in the oral cavity, or healthy patients. Anxiety was independently associated with a 123.8 times greater risk of having BMS.
2021 July/August; 69(4):46-52.
-
Basic Science An extrapyramidal reaction presenting as an acute temporomandibular episode: a case report
William R. BachandFull Article (PDF)
A patient with sudden onset of severe jaw muscle spasms, facial grimacing, and difficulty speaking was found to be experiencing an adverse reaction to prochlorperazine (Compazine), which can cause extrapyramidal reactions. This case highlights the importance of obtaining an accurate history and being aware of possible adverse effects of medications.
2021 July/August; 69(4):54-55.
-
Periodontics Applying basic math to periodontal decision-making
Ben BaleviFull Article (PDF)
This review provides an introduction to analysis of clinical measures of uncertainty and statistical concepts to aid clinicians in using evidence-based dentistry.
2021 July/August; 69(4):56-63.
-
Oral and Maxillofacial Surgery Quality of life of patients following orthognathic surgery
Gilberto HeinzmannFull Article (PDF)
João Paulo De Carli
Silvana Alba Scortegagna
Aline Hübner da Silva
Alexandra Oliveira Keller
Marcos Eugenio de Bittencourt
Julia Zandoná
Maria Salete Sandini Linden
This study evaluated the quality of life of 10 patients who had undergone orthognathic surgery for a dentofacial deformity. The patients answered a variety of questionnaires on their physical, functional, psychological, and social status after orthognathic surgery, and analysis revealed that surgery resulted in improved quality of life.
2021 July/August; 69(4):64-69.
-
Oral Medicine, Oral Diagnosis, Oral Pathology Probability of oral complications of radiotherapy and chemotherapy for head and neck cancer
Laís Heringer Mendes CoelhoFull Article (PDF)
Clarice Lima Alvares da Silva
Rebeca Cardoso Pedra
Lucas de Paula Lopes Rosado
Francielle Silvestre Verner
Sibele Nascimento de Aquino
An analysis of the records of 400 patients who underwent radiotherapy, chemotherapy, or both for head and neck cancer revealed that 199 patients experienced oral complications associated with treatment. The risk increased when both therapies were performed. Associations were also found between the use of tobacco or alcohol and the rate of oral complications.
2021 July/August; 69(4):70-74.
-
Implants Titanium versus ceramic implants for overdentures: a meta-analysis of prospective studies
Emily Vivianne Freitas da SilvaFull Article (PDF)
Betina Chiarelo Commar
Sandro Basso Bitencourt
Liliane da Rocha Bonatto
Daniela Micheline dos Santos
Ana Beatriz Bueno Carlini Bittencourt
Marcelo Coelho Goiato
The aim of this study was to compare the use of titanium and ceramic implants for overdentures in terms of their failure rates, surface treatments, and marginal bone loss (MBL). The literature was searched using the PubMed, Scopus, and Cochrane databases up to October 2019. Clinical studies in which ceramic and titanium implants for overdentures were compared in terms of their failure rates, surface treatments, and MBL were included in the meta-analysis. The meta-analysis was performed based on the Mantel-Haenszel and inverse variance methods using a fixed-effects model and 95% confidence intervals. A total of 2747 publications were identified after the exclusion of duplicate articles. Fifteen were selected for full-text reading, and 2 were included in the review. Each of the 2 studies initially enrolled 24 patients, and a total of 38 patients (mean age of 62 years) were evaluated at the 1-year follow-up. A total of 112 titanium implants (success rate of 71.1%) and 146 ceramic implants (success rate of 65.9%) were placed. Twenty titanium implants failed, and an associated MBL of 0.15 mm was observed. For ceramic implants, 42 failures occurred, and an associated MBL of 0.33 mm was observed. Titanium implants provided better clinical results (less MBL and lower failure rate) for the support of overdentures than did ceramic implants.
2021 July/August; 69(4):e1-e5.
2014
July/August 2021
Table of Contents
Departments
-
Editorial The greater good
Timothy F. KosinskiFull Article (PDF)
2021 July/August; 69(4):6.
-
Esthetics Minimally invasive correction of a fractured anterior crown using combination treatment
Wynn OkudaFull Article (PDF)
2021 July/August; 69(4):7-9.
-
Prosthodontics Conversion of a bar overdenture to an attachment-only overdenture
Samuel M. StrongFull Article (PDF)
2021 July/August; 69(4):10-13.
-
Pharmacology Tramadol: what have we learned in the last 25 years?
Mark DonaldsonFull Article (PDF)
Jason H. Goodchild
2021 July/August; 69(4):14-18.
-
Oral Diagnosis Unilocular maxillary lesion and Painless lump on the mandible
Galal OmamiFull Article (PDF)
2021 July/August; 69(4):76,78.
-
Self-Instruction Answers Exercises No. GD459, GD460, and GD461 from the July/August 2020 issue
2021 July/August; 69(4):79.Full Article (PDF)
Clinical Articles
-
SELF-INSTRUCTION
Basic Science Evaluation of a mucoadhesive pilocarpine tablet for the treatment of xerostomia: a randomized, double-blind, crossover clinical trial
George Mário de Araújo Silva GusmãoFull Article (PDF)
Patrícia Mendonça Borba
Marcela de Aguiar Galindo
Laura de Fátima Souto Maior
Luiz Alcino Monteiro Gueiros
Jair Carneiro Leão
José Lamartine Soares Sobrinho
Alessandra de Albuquerque Tavares Carvalho
A randomized, double-blind, crossover clinical trial was conducted to evaluate the effectiveness of a mucoadhesive, controlled-release tablet of pilocarpine for the treatment of xerostomia in older adults. Tablets with or without pilocarpine relieved patients’ dry mouth symptoms and increased unstimulated salivary flow, but stimulated salivary flow was increased only when tablets containing pilocarpine were administered.
2021 July/August; 69(4):19-26.
Self-Instruction Exercise No. GD477 -
SELF-INSTRUCTION
Restorative Dentistry Use of smartphones and tablets in radiographic evaluation: accuracy of caries detection on bitewing radiographs
Cristinne Andrade MeloFull Article (PDF)
Marcos Antônio Lima dos Santos
Liciane dos Santos Menezes
Francielle Santos de Santana
Maria de Fátima Batista de Melo
Wilton Mitsunari Takeshita
This study compared the accuracy of tablet and smartphone displays to that of a calibrated LCD monitor for the detection of incipient caries on bitewing radiographs. The Pavilion dm1 notebook computer, iPhone 6s, Galaxy Gran2 Duos, iPad, and Galaxy Tab did not present statistically significant differences in diagnostic accuracy, suggesting that all of these displays can be used to detect incipient caries on bitewing radiographs.
2021 July/August; 69(4):28-34.
Self-Instruction Exercise No. GD478 -
Special Patient Care Pretransplantation and posttransplantation considerations in the oral healthcare of a patient with non-Hodgkin B-cell lymphoma: a case report
Ross TeicherFull Article (PDF)
Marc Henschel
This case report discusses considerations for oral rehabilitative treatment before and after hematopoietic stem cell transplantation in patients with non-Hodgkin B-cell lymphoma. The patient’s complicated medical history made dental treatment difficult, but careful attention to known considerations for patients undergoing stem cell therapy ensured maintenance of the patient’s oral health.
2021 July/August; 69(4):36-40.
-
SELF-INSTRUCTION
Esthetics/Cosmetic Dentistry Conservative approach to treating severe tetracycline staining: a 12-month follow-up
Rafael Santos RochaFull Article (PDF)
Maurício Yugo de Souza
Victor Ruano
Eduardo Bresciani
This case report describes minimally invasive treatment with a combination of at-home and in-office dental bleaching and direct restorations to improve the esthetics of tetracycline-stained teeth in a 44-year-old woman.
2021 July/August; 69(4):41-44.
Self-Instruction Exercise No. GD479 -
Special Patient Care Association of anxiety, depression, and stress with burning mouth syndrome: a case-control study
Cássia Emanuella Nóbrega MaltaFull Article (PDF)
Fábio Wildson Gurgel Costa
Camila Costa Dias
Anna Clara Aragão Matos Carlos
Fabrício Bitu Sousa
Paulo Goberlânio de Barros Silva
Carolina Rodrigues Teófilo
Burning mouth syndrome (BMS) is a painful disorder involving severe burning in the oral cavity in the absence of clinical signs. In this study, 60 patients were allocated to 3 groups: patients with BMS, patients with benign changes in the oral cavity, or healthy patients. Anxiety was independently associated with a 123.8 times greater risk of having BMS.
2021 July/August; 69(4):46-52.
-
Basic Science An extrapyramidal reaction presenting as an acute temporomandibular episode: a case report
William R. BachandFull Article (PDF)
A patient with sudden onset of severe jaw muscle spasms, facial grimacing, and difficulty speaking was found to be experiencing an adverse reaction to prochlorperazine (Compazine), which can cause extrapyramidal reactions. This case highlights the importance of obtaining an accurate history and being aware of possible adverse effects of medications.
2021 July/August; 69(4):54-55.
-
Periodontics Applying basic math to periodontal decision-making
Ben BaleviFull Article (PDF)
This review provides an introduction to analysis of clinical measures of uncertainty and statistical concepts to aid clinicians in using evidence-based dentistry.
2021 July/August; 69(4):56-63.
-
Oral and Maxillofacial Surgery Quality of life of patients following orthognathic surgery
Gilberto HeinzmannFull Article (PDF)
João Paulo De Carli
Silvana Alba Scortegagna
Aline Hübner da Silva
Alexandra Oliveira Keller
Marcos Eugenio de Bittencourt
Julia Zandoná
Maria Salete Sandini Linden
This study evaluated the quality of life of 10 patients who had undergone orthognathic surgery for a dentofacial deformity. The patients answered a variety of questionnaires on their physical, functional, psychological, and social status after orthognathic surgery, and analysis revealed that surgery resulted in improved quality of life.
2021 July/August; 69(4):64-69.
-
Oral Medicine, Oral Diagnosis, Oral Pathology Probability of oral complications of radiotherapy and chemotherapy for head and neck cancer
Laís Heringer Mendes CoelhoFull Article (PDF)
Clarice Lima Alvares da Silva
Rebeca Cardoso Pedra
Lucas de Paula Lopes Rosado
Francielle Silvestre Verner
Sibele Nascimento de Aquino
An analysis of the records of 400 patients who underwent radiotherapy, chemotherapy, or both for head and neck cancer revealed that 199 patients experienced oral complications associated with treatment. The risk increased when both therapies were performed. Associations were also found between the use of tobacco or alcohol and the rate of oral complications.
2021 July/August; 69(4):70-74.
-
Implants Titanium versus ceramic implants for overdentures: a meta-analysis of prospective studies
Emily Vivianne Freitas da SilvaFull Article (PDF)
Betina Chiarelo Commar
Sandro Basso Bitencourt
Liliane da Rocha Bonatto
Daniela Micheline dos Santos
Ana Beatriz Bueno Carlini Bittencourt
Marcelo Coelho Goiato
The aim of this study was to compare the use of titanium and ceramic implants for overdentures in terms of their failure rates, surface treatments, and marginal bone loss (MBL). The literature was searched using the PubMed, Scopus, and Cochrane databases up to October 2019. Clinical studies in which ceramic and titanium implants for overdentures were compared in terms of their failure rates, surface treatments, and MBL were included in the meta-analysis. The meta-analysis was performed based on the Mantel-Haenszel and inverse variance methods using a fixed-effects model and 95% confidence intervals. A total of 2747 publications were identified after the exclusion of duplicate articles. Fifteen were selected for full-text reading, and 2 were included in the review. Each of the 2 studies initially enrolled 24 patients, and a total of 38 patients (mean age of 62 years) were evaluated at the 1-year follow-up. A total of 112 titanium implants (success rate of 71.1%) and 146 ceramic implants (success rate of 65.9%) were placed. Twenty titanium implants failed, and an associated MBL of 0.15 mm was observed. For ceramic implants, 42 failures occurred, and an associated MBL of 0.33 mm was observed. Titanium implants provided better clinical results (less MBL and lower failure rate) for the support of overdentures than did ceramic implants.
2021 July/August; 69(4):e1-e5.
2013
July/August 2021
Table of Contents
Departments
-
Editorial The greater good
Timothy F. KosinskiFull Article (PDF)
2021 July/August; 69(4):6.
-
Esthetics Minimally invasive correction of a fractured anterior crown using combination treatment
Wynn OkudaFull Article (PDF)
2021 July/August; 69(4):7-9.
-
Prosthodontics Conversion of a bar overdenture to an attachment-only overdenture
Samuel M. StrongFull Article (PDF)
2021 July/August; 69(4):10-13.
-
Pharmacology Tramadol: what have we learned in the last 25 years?
Mark DonaldsonFull Article (PDF)
Jason H. Goodchild
2021 July/August; 69(4):14-18.
-
Oral Diagnosis Unilocular maxillary lesion and Painless lump on the mandible
Galal OmamiFull Article (PDF)
2021 July/August; 69(4):76,78.
-
Self-Instruction Answers Exercises No. GD459, GD460, and GD461 from the July/August 2020 issue
2021 July/August; 69(4):79.Full Article (PDF)
Clinical Articles
-
SELF-INSTRUCTION
Basic Science Evaluation of a mucoadhesive pilocarpine tablet for the treatment of xerostomia: a randomized, double-blind, crossover clinical trial
George Mário de Araújo Silva GusmãoFull Article (PDF)
Patrícia Mendonça Borba
Marcela de Aguiar Galindo
Laura de Fátima Souto Maior
Luiz Alcino Monteiro Gueiros
Jair Carneiro Leão
José Lamartine Soares Sobrinho
Alessandra de Albuquerque Tavares Carvalho
A randomized, double-blind, crossover clinical trial was conducted to evaluate the effectiveness of a mucoadhesive, controlled-release tablet of pilocarpine for the treatment of xerostomia in older adults. Tablets with or without pilocarpine relieved patients’ dry mouth symptoms and increased unstimulated salivary flow, but stimulated salivary flow was increased only when tablets containing pilocarpine were administered.
2021 July/August; 69(4):19-26.
Self-Instruction Exercise No. GD477 -
SELF-INSTRUCTION
Restorative Dentistry Use of smartphones and tablets in radiographic evaluation: accuracy of caries detection on bitewing radiographs
Cristinne Andrade MeloFull Article (PDF)
Marcos Antônio Lima dos Santos
Liciane dos Santos Menezes
Francielle Santos de Santana
Maria de Fátima Batista de Melo
Wilton Mitsunari Takeshita
This study compared the accuracy of tablet and smartphone displays to that of a calibrated LCD monitor for the detection of incipient caries on bitewing radiographs. The Pavilion dm1 notebook computer, iPhone 6s, Galaxy Gran2 Duos, iPad, and Galaxy Tab did not present statistically significant differences in diagnostic accuracy, suggesting that all of these displays can be used to detect incipient caries on bitewing radiographs.
2021 July/August; 69(4):28-34.
Self-Instruction Exercise No. GD478 -
Special Patient Care Pretransplantation and posttransplantation considerations in the oral healthcare of a patient with non-Hodgkin B-cell lymphoma: a case report
Ross TeicherFull Article (PDF)
Marc Henschel
This case report discusses considerations for oral rehabilitative treatment before and after hematopoietic stem cell transplantation in patients with non-Hodgkin B-cell lymphoma. The patient’s complicated medical history made dental treatment difficult, but careful attention to known considerations for patients undergoing stem cell therapy ensured maintenance of the patient’s oral health.
2021 July/August; 69(4):36-40.
-
SELF-INSTRUCTION
Esthetics/Cosmetic Dentistry Conservative approach to treating severe tetracycline staining: a 12-month follow-up
Rafael Santos RochaFull Article (PDF)
Maurício Yugo de Souza
Victor Ruano
Eduardo Bresciani
This case report describes minimally invasive treatment with a combination of at-home and in-office dental bleaching and direct restorations to improve the esthetics of tetracycline-stained teeth in a 44-year-old woman.
2021 July/August; 69(4):41-44.
Self-Instruction Exercise No. GD479 -
Special Patient Care Association of anxiety, depression, and stress with burning mouth syndrome: a case-control study
Cássia Emanuella Nóbrega MaltaFull Article (PDF)
Fábio Wildson Gurgel Costa
Camila Costa Dias
Anna Clara Aragão Matos Carlos
Fabrício Bitu Sousa
Paulo Goberlânio de Barros Silva
Carolina Rodrigues Teófilo
Burning mouth syndrome (BMS) is a painful disorder involving severe burning in the oral cavity in the absence of clinical signs. In this study, 60 patients were allocated to 3 groups: patients with BMS, patients with benign changes in the oral cavity, or healthy patients. Anxiety was independently associated with a 123.8 times greater risk of having BMS.
2021 July/August; 69(4):46-52.
-
Basic Science An extrapyramidal reaction presenting as an acute temporomandibular episode: a case report
William R. BachandFull Article (PDF)
A patient with sudden onset of severe jaw muscle spasms, facial grimacing, and difficulty speaking was found to be experiencing an adverse reaction to prochlorperazine (Compazine), which can cause extrapyramidal reactions. This case highlights the importance of obtaining an accurate history and being aware of possible adverse effects of medications.
2021 July/August; 69(4):54-55.
-
Periodontics Applying basic math to periodontal decision-making
Ben BaleviFull Article (PDF)
This review provides an introduction to analysis of clinical measures of uncertainty and statistical concepts to aid clinicians in using evidence-based dentistry.
2021 July/August; 69(4):56-63.
-
Oral and Maxillofacial Surgery Quality of life of patients following orthognathic surgery
Gilberto HeinzmannFull Article (PDF)
João Paulo De Carli
Silvana Alba Scortegagna
Aline Hübner da Silva
Alexandra Oliveira Keller
Marcos Eugenio de Bittencourt
Julia Zandoná
Maria Salete Sandini Linden
This study evaluated the quality of life of 10 patients who had undergone orthognathic surgery for a dentofacial deformity. The patients answered a variety of questionnaires on their physical, functional, psychological, and social status after orthognathic surgery, and analysis revealed that surgery resulted in improved quality of life.
2021 July/August; 69(4):64-69.
-
Oral Medicine, Oral Diagnosis, Oral Pathology Probability of oral complications of radiotherapy and chemotherapy for head and neck cancer
Laís Heringer Mendes CoelhoFull Article (PDF)
Clarice Lima Alvares da Silva
Rebeca Cardoso Pedra
Lucas de Paula Lopes Rosado
Francielle Silvestre Verner
Sibele Nascimento de Aquino
An analysis of the records of 400 patients who underwent radiotherapy, chemotherapy, or both for head and neck cancer revealed that 199 patients experienced oral complications associated with treatment. The risk increased when both therapies were performed. Associations were also found between the use of tobacco or alcohol and the rate of oral complications.
2021 July/August; 69(4):70-74.
-
Implants Titanium versus ceramic implants for overdentures: a meta-analysis of prospective studies
Emily Vivianne Freitas da SilvaFull Article (PDF)
Betina Chiarelo Commar
Sandro Basso Bitencourt
Liliane da Rocha Bonatto
Daniela Micheline dos Santos
Ana Beatriz Bueno Carlini Bittencourt
Marcelo Coelho Goiato
The aim of this study was to compare the use of titanium and ceramic implants for overdentures in terms of their failure rates, surface treatments, and marginal bone loss (MBL). The literature was searched using the PubMed, Scopus, and Cochrane databases up to October 2019. Clinical studies in which ceramic and titanium implants for overdentures were compared in terms of their failure rates, surface treatments, and MBL were included in the meta-analysis. The meta-analysis was performed based on the Mantel-Haenszel and inverse variance methods using a fixed-effects model and 95% confidence intervals. A total of 2747 publications were identified after the exclusion of duplicate articles. Fifteen were selected for full-text reading, and 2 were included in the review. Each of the 2 studies initially enrolled 24 patients, and a total of 38 patients (mean age of 62 years) were evaluated at the 1-year follow-up. A total of 112 titanium implants (success rate of 71.1%) and 146 ceramic implants (success rate of 65.9%) were placed. Twenty titanium implants failed, and an associated MBL of 0.15 mm was observed. For ceramic implants, 42 failures occurred, and an associated MBL of 0.33 mm was observed. Titanium implants provided better clinical results (less MBL and lower failure rate) for the support of overdentures than did ceramic implants.
2021 July/August; 69(4):e1-e5.
2012
July/August 2021
Table of Contents
Departments
-
Editorial The greater good
Timothy F. KosinskiFull Article (PDF)
2021 July/August; 69(4):6.
-
Esthetics Minimally invasive correction of a fractured anterior crown using combination treatment
Wynn OkudaFull Article (PDF)
2021 July/August; 69(4):7-9.
-
Prosthodontics Conversion of a bar overdenture to an attachment-only overdenture
Samuel M. StrongFull Article (PDF)
2021 July/August; 69(4):10-13.
-
Pharmacology Tramadol: what have we learned in the last 25 years?
Mark DonaldsonFull Article (PDF)
Jason H. Goodchild
2021 July/August; 69(4):14-18.
-
Oral Diagnosis Unilocular maxillary lesion and Painless lump on the mandible
Galal OmamiFull Article (PDF)
2021 July/August; 69(4):76,78.
-
Self-Instruction Answers Exercises No. GD459, GD460, and GD461 from the July/August 2020 issue
2021 July/August; 69(4):79.Full Article (PDF)
Clinical Articles
-
SELF-INSTRUCTION
Basic Science Evaluation of a mucoadhesive pilocarpine tablet for the treatment of xerostomia: a randomized, double-blind, crossover clinical trial
George Mário de Araújo Silva GusmãoFull Article (PDF)
Patrícia Mendonça Borba
Marcela de Aguiar Galindo
Laura de Fátima Souto Maior
Luiz Alcino Monteiro Gueiros
Jair Carneiro Leão
José Lamartine Soares Sobrinho
Alessandra de Albuquerque Tavares Carvalho
A randomized, double-blind, crossover clinical trial was conducted to evaluate the effectiveness of a mucoadhesive, controlled-release tablet of pilocarpine for the treatment of xerostomia in older adults. Tablets with or without pilocarpine relieved patients’ dry mouth symptoms and increased unstimulated salivary flow, but stimulated salivary flow was increased only when tablets containing pilocarpine were administered.
2021 July/August; 69(4):19-26.
Self-Instruction Exercise No. GD477 -
SELF-INSTRUCTION
Restorative Dentistry Use of smartphones and tablets in radiographic evaluation: accuracy of caries detection on bitewing radiographs
Cristinne Andrade MeloFull Article (PDF)
Marcos Antônio Lima dos Santos
Liciane dos Santos Menezes
Francielle Santos de Santana
Maria de Fátima Batista de Melo
Wilton Mitsunari Takeshita
This study compared the accuracy of tablet and smartphone displays to that of a calibrated LCD monitor for the detection of incipient caries on bitewing radiographs. The Pavilion dm1 notebook computer, iPhone 6s, Galaxy Gran2 Duos, iPad, and Galaxy Tab did not present statistically significant differences in diagnostic accuracy, suggesting that all of these displays can be used to detect incipient caries on bitewing radiographs.
2021 July/August; 69(4):28-34.
Self-Instruction Exercise No. GD478 -
Special Patient Care Pretransplantation and posttransplantation considerations in the oral healthcare of a patient with non-Hodgkin B-cell lymphoma: a case report
Ross TeicherFull Article (PDF)
Marc Henschel
This case report discusses considerations for oral rehabilitative treatment before and after hematopoietic stem cell transplantation in patients with non-Hodgkin B-cell lymphoma. The patient’s complicated medical history made dental treatment difficult, but careful attention to known considerations for patients undergoing stem cell therapy ensured maintenance of the patient’s oral health.
2021 July/August; 69(4):36-40.
-
SELF-INSTRUCTION
Esthetics/Cosmetic Dentistry Conservative approach to treating severe tetracycline staining: a 12-month follow-up
Rafael Santos RochaFull Article (PDF)
Maurício Yugo de Souza
Victor Ruano
Eduardo Bresciani
This case report describes minimally invasive treatment with a combination of at-home and in-office dental bleaching and direct restorations to improve the esthetics of tetracycline-stained teeth in a 44-year-old woman.
2021 July/August; 69(4):41-44.
Self-Instruction Exercise No. GD479 -
Special Patient Care Association of anxiety, depression, and stress with burning mouth syndrome: a case-control study
Cássia Emanuella Nóbrega MaltaFull Article (PDF)
Fábio Wildson Gurgel Costa
Camila Costa Dias
Anna Clara Aragão Matos Carlos
Fabrício Bitu Sousa
Paulo Goberlânio de Barros Silva
Carolina Rodrigues Teófilo
Burning mouth syndrome (BMS) is a painful disorder involving severe burning in the oral cavity in the absence of clinical signs. In this study, 60 patients were allocated to 3 groups: patients with BMS, patients with benign changes in the oral cavity, or healthy patients. Anxiety was independently associated with a 123.8 times greater risk of having BMS.
2021 July/August; 69(4):46-52.
-
Basic Science An extrapyramidal reaction presenting as an acute temporomandibular episode: a case report
William R. BachandFull Article (PDF)
A patient with sudden onset of severe jaw muscle spasms, facial grimacing, and difficulty speaking was found to be experiencing an adverse reaction to prochlorperazine (Compazine), which can cause extrapyramidal reactions. This case highlights the importance of obtaining an accurate history and being aware of possible adverse effects of medications.
2021 July/August; 69(4):54-55.
-
Periodontics Applying basic math to periodontal decision-making
Ben BaleviFull Article (PDF)
This review provides an introduction to analysis of clinical measures of uncertainty and statistical concepts to aid clinicians in using evidence-based dentistry.
2021 July/August; 69(4):56-63.
-
Oral and Maxillofacial Surgery Quality of life of patients following orthognathic surgery
Gilberto HeinzmannFull Article (PDF)
João Paulo De Carli
Silvana Alba Scortegagna
Aline Hübner da Silva
Alexandra Oliveira Keller
Marcos Eugenio de Bittencourt
Julia Zandoná
Maria Salete Sandini Linden
This study evaluated the quality of life of 10 patients who had undergone orthognathic surgery for a dentofacial deformity. The patients answered a variety of questionnaires on their physical, functional, psychological, and social status after orthognathic surgery, and analysis revealed that surgery resulted in improved quality of life.
2021 July/August; 69(4):64-69.
-
Oral Medicine, Oral Diagnosis, Oral Pathology Probability of oral complications of radiotherapy and chemotherapy for head and neck cancer
Laís Heringer Mendes CoelhoFull Article (PDF)
Clarice Lima Alvares da Silva
Rebeca Cardoso Pedra
Lucas de Paula Lopes Rosado
Francielle Silvestre Verner
Sibele Nascimento de Aquino
An analysis of the records of 400 patients who underwent radiotherapy, chemotherapy, or both for head and neck cancer revealed that 199 patients experienced oral complications associated with treatment. The risk increased when both therapies were performed. Associations were also found between the use of tobacco or alcohol and the rate of oral complications.
2021 July/August; 69(4):70-74.
-
Implants Titanium versus ceramic implants for overdentures: a meta-analysis of prospective studies
Emily Vivianne Freitas da SilvaFull Article (PDF)
Betina Chiarelo Commar
Sandro Basso Bitencourt
Liliane da Rocha Bonatto
Daniela Micheline dos Santos
Ana Beatriz Bueno Carlini Bittencourt
Marcelo Coelho Goiato
The aim of this study was to compare the use of titanium and ceramic implants for overdentures in terms of their failure rates, surface treatments, and marginal bone loss (MBL). The literature was searched using the PubMed, Scopus, and Cochrane databases up to October 2019. Clinical studies in which ceramic and titanium implants for overdentures were compared in terms of their failure rates, surface treatments, and MBL were included in the meta-analysis. The meta-analysis was performed based on the Mantel-Haenszel and inverse variance methods using a fixed-effects model and 95% confidence intervals. A total of 2747 publications were identified after the exclusion of duplicate articles. Fifteen were selected for full-text reading, and 2 were included in the review. Each of the 2 studies initially enrolled 24 patients, and a total of 38 patients (mean age of 62 years) were evaluated at the 1-year follow-up. A total of 112 titanium implants (success rate of 71.1%) and 146 ceramic implants (success rate of 65.9%) were placed. Twenty titanium implants failed, and an associated MBL of 0.15 mm was observed. For ceramic implants, 42 failures occurred, and an associated MBL of 0.33 mm was observed. Titanium implants provided better clinical results (less MBL and lower failure rate) for the support of overdentures than did ceramic implants.
2021 July/August; 69(4):e1-e5.