Sebastian Ciancio, DDS
Full Name Sebastian Ciancio, DDS
Phone (716) 829-3848
Fax (716) 837-7623
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Speaker Biography

Sebastian G. Ciancio, DDS, is Distinguished Service Professor and Chair of the Dept. of Periodontics and Endodontics, Adjunct Professor of Pharmacology at the University at Buffalo, State University of New York, Schools of Medicine and Dental Medicine. He also is Director of the Center for Dental Studies at the University at Buffalo, diplomate of the American Board of Periodontology, past president of the American Academy of Periodontology and its Foundation, Immediate Past President, International Academy of Periodontology and author of over 150 scientific papers related to clinical periodontics and pharmacology. He is a member of the United States Pharmacopea Council of Dental Experts, and Editor of the ADA Guide to Dental Therapeutics. He has received a number of national honors and is a recipient of the Distinguished Scientist Award in Pharmacology from the International Assn. for Dental Research.

Course Descriptions

Title: Drug Interactions: Impact on Dental Practice

As our population ages, our patients are taking increasing numbers of medications, both prescribed and over-the counter products. All medications have a known risk/benefit ratio. Taking one or more drugs that interact may change this risk benefit ratio. This presentation is designed to provide dental practitioners with an understanding of drug interactions and mechanisms by which they occur and the role of liver metabolism in controlling many interactions. Emphasis will be placed on drugs prescribed by dental practitioners. Clinical examples of drug antagonism and synergism associated with commonly prescribed dental medications will be presented. Upon completion of this presentation, dentists will be able to understand the fundamentals of drug interactions and be able to minimize them in their practice.

Title: Lotions, Potions, Pastes and More!

When patients ask “What products should I use for better oral health, dental practitioners should be able to provide evidence based answers! When they are taking a variety of medications and present with changes in oral tissues, are these changes medication related? Over-the-counter and prescription drugs are used frequently, in large quantities and by many adults. As our population ages, the use of medications increases significantly . A number of these medications may impact oral health which in turn can affect general health. In view of this dental professionals and patients can expect to encounter oral side effects from use of their medications. Practitioners must be aware of medication related problems and their impact on diagosis and treatment planning of dental health problems. Also patients must be cognizant of these potential adverse effects on their oral health so that they can seek appropriate care as soon as possible. This program is designed to help dental practitioners become knowledgeable about oral manfestations of systemic agents as well as on the latest therapeutic, non-prescription oral healthcare products, including mouthrinses and herbal agents.

Title: Perio-Advanaces: Impact on Clinical Practice

Periodontics is the meeting ground of science and art in dentistry. Are your patients and your practice benefiting by knowledge of the latest therapeutic concepts available for use in the treatment of periodontal disease and implants ? This program will detail the application of new knowledge to periodontal practice in such areas as management of implants, arrest of disease and surgical regeneration of periodontal tissues. The maintenance of periodontal health around natural teeth as well as implants will be discussed with emphasis on medication related factors affecting relapse such as xerostomia and other medication related problems. In addition, the interaction between periodontal disease and systemic disease will be reviewed.

Title: Medications: Impact on Periodontal Diagnosis and Treatement Planning

As our population ages, they will be taking more medications which may benefit their general health but not necessarily their oral health. The effect of medications have been grouped into categories as follows: behavioral alteration of oral hygiene methods by sedatives, tranquilizers and antihypertensives; alteration of plaque composition by agents causing xerostomia as well as chewable medications, liquid preparations and antacids; effect on gingival tissues of Phenytoin, calcium channel blockers and cyclosporine; effect on gingival crevicular fluid and salivary flow since over 400 medications cause xerostomia as a side effect; and agents with effects on oral mucosa such as minocycline and oral contraceptives. Although most medications to be discussed increase the risk for loss of alveolar bone, a few may decrease the risk as follows: effect of phenytoin (dilantin) on alveolar bone, the antibacterial effect of antibiotics, the anticollagenolytic effects of tetracyclines, and the effect of non-steroidal anti-inflammatory drugs on decreasing alveolar bone resorption. Dentists must always take thorough medical histories and be aware of medication-related problems and their effect on diagnosis and treatment planning. This presentation identifies and describes drugs that may affect oral health and presents clinical management information relative to these patients.


Are your patients and your practice benefiting by knowledge of the latest therapeutic concepts available for use in the prevention and treatment of periodontal disease? This program will detail the application of new knowledge to periodontal practice in such areas as diagnostics, arrest of disease and regeneration. Also, the program will provide the practitioner with a clinical understanding of the various medications, both locally placed and systemically administered as adjuncts to periodontal therapy. The maintenance of periodontal and implant health will be discussed with the emphasis on factors affecting relapse, as well as the interaction between periodontal and systemic disease.


-advances in treatment of periodontal disease
-pro’s and con’s of local and systemic medications
-factors affecting maintenance of teeth and implants
-about attached gingival and implant success

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Drugs and Interactions
Periochemotherapeutics in the 21st Centurt